💊 Product Overview
Brand Name: Valtoco
Generic Name: Diazepam Nasal Spray
Manufacturer: Neurelis, Inc.
Formulation: Single-use nasal spray device (available in 5 mg, 10 mg, 15 mg, 20 mg doses)
Controlled Substance: Schedule IV (CIV)
⚗️ Pharmacology
Active Ingredient: Diazepam (CAS 439‑14‑5)
Mechanism: Benzodiazepine that enhances GABA activity in the brain, producing anticonvulsant, anxiolytic, and sedative effects.
Onset: Rapid absorption through nasal mucosa; peak plasma concentration within 1 hour.
🧠 Clinical Use
Indication: Acute treatment of seizure clusters in patients ≥ 6 years old with epilepsy.
Administration: Intranasal — one spray per nostril depending on prescribed dose.
Storage: Room temperature 20–25 °C (68–77 °F).
⚠️ Safety Notes
Common Side Effects: Drowsiness, nasal discomfort, headache.
Precautions: Avoid concurrent CNS depressants (e.g., opioids, alcohol).
Dependence Risk: Low but possible with prolonged benzodiazepine exposure.